gnpl_a_1399391_sm9119.pdf (597.34 kB)
A new bischromanone from the stems of Semecarpus caudata
journal contribution
posted on 2017-11-09, 07:16 authored by Phu H. Dang, Tinh T. Nguyen, Tho H. Le, Hai X. Nguyen, Mai T. T. Nguyen, Nhan T. NguyenFrom an CHCl3-soluble fraction of the stems of Semecarpus caudata, one new bischromanone named semecarpanone (1), together with 5 known flavonoids (2–6) were isolated. Their structures were elucidated based on interpretation of spectroscopic data. The stereo-configuration of 1 was identified based on the calculated and experimental coupling constants. Compounds 4–6 showed potent tyrosinase inhibitory activity with the IC50 values ranging from 15.0 to 76.3 μM.