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A facile one-pot three-component synthesis of benzylideneamino-3,5-dimethyl-1H-pyrazoles

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posted on 2018-06-18, 21:33 authored by Parameshwara Chary Jilloju, Rajeswar Rao Vedula

A facile, one-pot three-component protocol for the synthesis of substituted 4-(benzylideneamino)-5-(3,5-dimethyl-1H-pyrazol-1-yl)-4H-1,2,4-triazole-3-thiols have been reported by the reaction of 4-amino-5-hydrazinyl-4H-1,2,4-triazole-3-thiol with acetyl acetone and various substituted benzaldehydes via multi component reaction. The newly synthesized derivatives were characterized by their elemental analysis and spectral data. The current strategy provides heterocyclic compounds in good yields with broad substrate scope.

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The authors are thankful to the Director, National Institute of Technology, Warangal, Telangana State, India for providing facilities and financial support.

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