ol5b01102_si_001.pdf (4.79 MB)
A Non-Cross-Coupling Approach to Arene-Bridged Macrocycles: Synthesis, Structure, and Direct, Regioselective Functionalization of a Cycloparaphenylene Fragment
journal contribution
posted on 2015-12-17, 08:23 authored by Nirmal
K. Mitra, Rolande Meudom, John D. Gorden, Bradley L. MernerA new
synthetic strategy that employs a relatively unstrained,
1,4-diketo-bridged macrocycle as a precursor to a strained, 1,4-arene-bridged
(bent para-phenylene) macrocycle has been developed.
The distorted p-terphenyl nucleus (CPP fragment)
of the macrocycle has been characterized by X-ray crystallography,
and a direct, regioselective bromination protocol of the macrocyclic
system is reported.