10.1371/journal.pone.0094380.g002 Nguyen Thuy Duong Nguyen Thuy Duong Glenn E. Morris Glenn E. Morris Le Thanh Lam Le Thanh Lam Qiuping Zhang Qiuping Zhang Caroline A. Sewry Caroline A. Sewry Catherine M. Shanahan Catherine M. Shanahan Ian Holt Ian Holt Tissue-specific expression of giant and alpha isoforms of nesprins. Public Library of Science 2014 cell biology Cellular structures and organelles Cell membranes Membrane proteins Transmembrane proteins Molecular cell biology Biochemistry dna DNA amplification proteins Structural proteins rna RNA synthesis Nucleic acids immunology immunochemistry genetics gene expression Gene regulation Genetic dominance Autosomal dominant traits Human genetics Molecular genetics cardiology Cardiovascular diseases cardiomyopathies neurology Muscular dystrophies alpha isoforms 2014-04-09 03:41:15 Figure https://plos.figshare.com/articles/figure/_Tissue_specific_expression_of_giant_and_alpha_isoforms_of_nesprins_/993469 <p>Quantitative PCR to show mRNA expression of nesprin isoforms relative to the expression of two endogenous house-keeping controls. Charts represent the mean relative expression ± SEM, measured in cDNA preparations from 20 human tissues and 7 cell lines. These values are given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0094380#pone.0094380.s001" target="_blank">Tables S3 and S4 in File S1</a>. Bar charts show relative expression of (A) nesprin-1-giant and nesprin-2-giant, and (B) nesprin-1-alpha-2 and nesprin-2-alpha-1.</p>