%0 Figure %A T. Davis, Bryan %A Wang, Xiao-Jun %A A. Rohret, Judy %A T. Struzynski, Jason %A P. Merricks, Elizabeth %A A. Bellinger, Dwight %A A. Rohret, Frank %A C. Nichols, Timothy %A S. Rogers, Christopher %D 2014 %T Coronary artery atherosclerosis in 11-month-old LDLR−/−, LDLR +/−, and LDLR +/+ pigs fed a high fat, high cholesterol diet. %U https://plos.figshare.com/articles/figure/_Coronary_artery_atherosclerosis_in_11_month_old_LDLR_8722_8722_LDLR_8722_and_LDLR_pigs_fed_a_high_fat_high_cholesterol_diet_/980095 %R 10.1371/journal.pone.0093457.g005 %2 https://ndownloader.figshare.com/files/1442223 %K biotechnology %K cell biology %K Molecular cell biology %K genetics %K Genetic dominance %K Autosomal dominant diseases %K Familial hypercholesterolemia %K Autosomal dominant traits %K Animal genetics %K Genetics of disease %K Human genetics %K molecular biology %K Molecular biology techniques %K cloning %K Organismal cloning %K Veterinary science %K Animal types %K Large animals %K cardiology %K Vascular medicine %K atherosclerosis %K Model organisms %K Animal models %K artery %K 11-month-old %K ldlr %K pigs %K fed %X

Representative H&E stained sections from each group are shown: LDLR−/− (A,B), LDLR +/− (C,D), and LDLR +/+ (E,F). Complex lesions were seen in the LDLR−/− pigs (A,B) that exhibited hemorrhage, possible areas of calcification, fibrous caps and foam cells.

%I PLOS ONE