10.1371/journal.pone.0093457.g005 Bryan T. Davis Bryan T. Davis Xiao-Jun Wang Xiao-Jun Wang Judy A. Rohret Judy A. Rohret Jason T. Struzynski Jason T. Struzynski Elizabeth P. Merricks Elizabeth P. Merricks Dwight A. Bellinger Dwight A. Bellinger Frank A. Rohret Frank A. Rohret Timothy C. Nichols Timothy C. Nichols Christopher S. Rogers Christopher S. Rogers Coronary artery atherosclerosis in 11-month-old <i>LDLR−/−, LDLR +/−,</i> and <i>LDLR +/+</i> pigs fed a high fat, high cholesterol diet. Public Library of Science 2014 biotechnology cell biology Molecular cell biology genetics Genetic dominance Autosomal dominant diseases Familial hypercholesterolemia Autosomal dominant traits Animal genetics Genetics of disease Human genetics molecular biology Molecular biology techniques cloning Organismal cloning Veterinary science Animal types Large animals cardiology Vascular medicine atherosclerosis Model organisms Animal models artery 11-month-old ldlr pigs fed 2014-04-01 03:19:01 Figure https://plos.figshare.com/articles/figure/_Coronary_artery_atherosclerosis_in_11_month_old_LDLR_8722_8722_LDLR_8722_and_LDLR_pigs_fed_a_high_fat_high_cholesterol_diet_/980095 <p>Representative H&E stained sections from each group are shown: <i>LDLR−/−</i> (A,B), <i>LDLR +/−</i> (C,D), and <i>LDLR +/+</i> (E,F). Complex lesions were seen in the <i>LDLR−/−</i> pigs (A,B) that exhibited hemorrhage, possible areas of calcification, fibrous caps and foam cells.</p>