10.1371/journal.pone.0093457.g005
Bryan T. Davis
Bryan
T. Davis
Xiao-Jun Wang
Xiao-Jun
Wang
Judy A. Rohret
Judy
A. Rohret
Jason T. Struzynski
Jason
T. Struzynski
Elizabeth P. Merricks
Elizabeth
P. Merricks
Dwight A. Bellinger
Dwight
A. Bellinger
Frank A. Rohret
Frank
A. Rohret
Timothy C. Nichols
Timothy
C. Nichols
Christopher S. Rogers
Christopher
S. Rogers
Coronary artery atherosclerosis in 11-month-old <i>LDLR−/−, LDLR +/−,</i> and <i>LDLR +/+</i> pigs fed a high fat, high cholesterol diet.
Public Library of Science
2014
biotechnology
cell biology
Molecular cell biology
genetics
Genetic dominance
Autosomal dominant diseases
Familial hypercholesterolemia
Autosomal dominant traits
Animal genetics
Genetics of disease
Human genetics
molecular biology
Molecular biology techniques
cloning
Organismal cloning
Veterinary science
Animal types
Large animals
cardiology
Vascular medicine
atherosclerosis
Model organisms
Animal models
artery
11-month-old
ldlr
pigs
fed
2014-04-01 03:19:01
Figure
https://plos.figshare.com/articles/figure/_Coronary_artery_atherosclerosis_in_11_month_old_LDLR_8722_8722_LDLR_8722_and_LDLR_pigs_fed_a_high_fat_high_cholesterol_diet_/980095
<p>Representative H&E stained sections from each group are shown: <i>LDLR−/−</i> (A,B), <i>LDLR +/−</i> (C,D), and <i>LDLR +/+</i> (E,F). Complex lesions were seen in the <i>LDLR−/−</i> pigs (A,B) that exhibited hemorrhage, possible areas of calcification, fibrous caps and foam cells.</p>