%0 Generic %A Islam, Rafique %A L. Kumimoto, Emily %A Bao, Hong %A Zhang, Bing %D 2012 %T Human SOD1 co-overexpressed in motoneurons and glial cells and treated with 3 mM BMAA. %U https://f1000.figshare.com/articles/dataset/Figure_5_Human_SOD1_co-overexpressed_in_motoneurons_and_glial_cells_and_treated_with_3_mM_BMAA_/97098 %R 10.6084/m9.figshare.97098.v1 %2 https://ndownloader.figshare.com/files/225264 %2 https://ndownloader.figshare.com/files/142951 %K paraquat %K SOD1 %K BMMA %K amyotrophic lateral sclerosis %K hydrogen peroxide %K Neuroscience %X

Shown are survival rates of 35 day-old male sod1 transgenic flies under 3 mM BMAA treatment. Panels A, B, and C represent flies expressing mutant human A4V, G85R, and wild type SOD1 proteins, respectively. Like 5 day-old time points (Figure 3, A-C), the SOD1 flies survived longer compared to the controls (CS and dSOD1). The 50% survival rate is increased by 10, 30 and 30% for A4V, G85R, wt SOD1, respectively, when compared to dSOD1 flies. Differences were considered statistically significant if p

%I f1000research.com