10.1021/acs.joc.9b01619.s003 Woohyeong Lee Woohyeong Lee Changhoon Shin Changhoon Shin Soo Eun Park Soo Eun Park Jung Min Joo Jung Min Joo Regio- and Stereoselective Synthesis of Thiazole-Containing Triarylethylenes by Hydroarylation of Alkynes American Chemical Society 2019 Hydroarylation moietie Thiazole-Containing Triarylethylenes C 5 selectivity Alkynes Thiazole-containing π- Stereoselective Synthesis trisubstituted olefins hydroarylation reaction carboxylic acids species thiazole-containing triarylethylenes oxazole Pd-catalyzed syn complex access Regio functionalization stereoselective syntheses pyrazole diaryl alkynes photochromic materials unsubstituted thiazole 2019-08-21 12:13:38 Dataset https://acs.figshare.com/articles/dataset/Regio-_and_Stereoselective_Synthesis_of_Thiazole-Containing_Triarylethylenes_by_Hydroarylation_of_Alkynes/9699551 Thiazole-containing π-conjugated moieties are important structural units in the development of new electronic and photochromic materials. We have developed a Pd-catalyzed <i>syn</i>-hydroarylation reaction of diaryl alkynes with thiazoles that provides access to thiazole-containing triarylethylenes. Pd­(II) complexes derived from Pd(0) species and carboxylic acids facilitated C–H functionalization of the unsubstituted thiazole with high C5 selectivity. The catalytic system was also compatible with other azoles, such as oxazoles and a pyrazole, allowing the stereoselective syntheses of various trisubstituted olefins.