10.1021/acs.joc.9b01619.s003
Woohyeong Lee
Woohyeong
Lee
Changhoon Shin
Changhoon
Shin
Soo Eun Park
Soo Eun
Park
Jung Min Joo
Jung Min
Joo
Regio- and Stereoselective
Synthesis of Thiazole-Containing
Triarylethylenes by Hydroarylation of Alkynes
American Chemical Society
2019
Hydroarylation
moietie
Thiazole-Containing Triarylethylenes
C 5 selectivity
Alkynes Thiazole-containing π-
Stereoselective Synthesis
trisubstituted olefins
hydroarylation reaction
carboxylic acids
species
thiazole-containing triarylethylenes
oxazole
Pd-catalyzed syn
complex
access
Regio
functionalization
stereoselective syntheses
pyrazole
diaryl alkynes
photochromic materials
unsubstituted thiazole
2019-08-21 12:13:38
Dataset
https://acs.figshare.com/articles/dataset/Regio-_and_Stereoselective_Synthesis_of_Thiazole-Containing_Triarylethylenes_by_Hydroarylation_of_Alkynes/9699551
Thiazole-containing
π-conjugated moieties are important structural
units in the development of new electronic and photochromic materials.
We have developed a Pd-catalyzed <i>syn</i>-hydroarylation
reaction of diaryl alkynes with thiazoles that provides access to
thiazole-containing triarylethylenes. Pd(II) complexes derived from
Pd(0) species and carboxylic acids facilitated C–H functionalization
of the unsubstituted thiazole with high C5 selectivity. The catalytic
system was also compatible with other azoles, such as oxazoles and
a pyrazole, allowing the stereoselective syntheses of various trisubstituted
olefins.