TY - DATA T1 - Specific 12α-hydroxylation of grandiflorenic acid by permeabilised fungus Fusarium graminearum PY - 2014/04/23 AU - Y. Ruan AU - B.J. Ma AU - L.Z. Li AU - X.L. Wang UR - https://tandf.figshare.com/articles/journal_contribution/Specific_12_hydroxylation_of_grandiflorenic_acid_by_permeabilised_fungus_i_Fusarium_graminearum_i_/969637 DO - 10.6084/m9.figshare.969637.v2 L4 - https://ndownloader.figshare.com/files/1471576 KW - grandiflorenic KW - permeabilised KW - fungus N2 - Biotransformation of grandiflorenic acid by permeabilised fungus Fusarium graminearum to yield its hydroxylation derivative, 12α-hydroxygrandiflorenic acid, was studied. The biotransformed product was isolated by column chromatography and its structure was determined by mass spectrum and nuclear magnetic resonance analysis. Grandiflorenic acid was efficiently metabolised by the fungus. After 72 h, the substrate was almost completely converted into the product. ER -