TY - DATA T1 - Features of Fv1. PY - 2014/03/06 AU - Melvyn W. Yap AU - Emily Colbeck AU - Scott A. Ellis AU - Jonathan P. Stoye UR - https://plos.figshare.com/articles/figure/_Features_of_Fv1_/954585 DO - 10.1371/journal.ppat.1003968.g001 L4 - https://ndownloader.figshare.com/files/1410959 KW - Evolutionary biology KW - Evolutionary genetics KW - genetics KW - Gene function KW - Genetic mutation KW - microbiology KW - Virology KW - Viral transmission and infection KW - Viral clearance KW - Animal models of infection KW - Viral replication KW - Virulence factors and mechanisms KW - Host-pathogen interaction N2 - At the top of the figure is a schematic of the Fv1 protein showing the relative positions of the previously mapped functional domains including coiled coil and major homology regions as well as the host range specificity regions previously defined by a comparison of Fv1n and Fv1b [48]. Below is shown the positions of four variable regions (VA–D), the amino acid differences that define them and the number of times each amino acid occurs. Based on a comparison of 19 mice (Table 1 plus Table 2). ER -