%0 Figure %A L. Van Sinderen, Michelle %A Steinberg, Gregory R. %A B. Jørgensen, Sebastian %A Q. To, Sarah %A C. Knower, Kevin %A D. Clyne, Colin %A Honeyman, Jane %A D. Chow, Jenny %A A. Herridge, Kerrie %A E. E. Jones, Margaret %A R. Simpson, Evan %A Chin Boon, Wah %D 2014 %T Six month-old male whole body glucose, insulin and pyruvate tolerance. %U https://plos.figshare.com/articles/figure/Six_month_old_male_whole_body_glucose_insulin_and_pyruvate_tolerance_/929330 %R 10.1371/journal.pone.0087230.g003 %2 https://ndownloader.figshare.com/files/1380084 %K Anatomy and physiology %K Endocrine system %K Endocrine physiology %K insulin %K Reproductive endocrinology %K Diabetic endocrinology %K Biochemistry %K hormones %K Model organisms %K Animal models %K mouse %K Endocrinology %K month-old %K pyruvate %X

Whole body tolerance tests were completed on fasted 6 month-old male wildtype (WT), aromatase knockout (KO) and 2.5 µg/kg 17β-estradiol-treated KO (KOE). (a) Glucose tolerance test and corresponding area under curve; (b) insulin tolerance test and corresponding area under curve; (c) pyruvate tolerance test and corresponding area under curve. Data are presented from replicate analysis (n =  shown on corresponding bar) as the mean ± SD. *p<0.05, **p<0.01, versus expression in age-matched WT samples and #p<0.05 and ##p<0.01 versus KO samples

%I PLOS ONE