10.1371/journal.pone.0082389.s001 Alexandru D. P. Papoiu Alexandru D. P. Papoiu Leigh A. Nattkemper Leigh A. Nattkemper Kristen M. Sanders Kristen M. Sanders Robert A. Kraft Robert A. Kraft Yiong-Huak Chan Yiong-Huak Chan Robert C. Coghill Robert C. Coghill Gil Yosipovitch Gil Yosipovitch Table S1 - Brain’s Reward Circuits Mediate Itch Relief. A Functional MRI Study of Active Scratching Public Library of Science 2013 circuits mediate itch mri 2013-12-06 03:27:49 Dataset https://plos.figshare.com/articles/dataset/_Brain_8217_s_Reward_Circuits_Mediate_Itch_Relief_A_Functional_MRI_Study_of_Active_Scratching_/871118 <p><b>Regions of interest involved in the brain processing of itch significantly impacted by scratching.</b> Brain areas correlated with itch relief and scratching pleasurability are shown. The highest Z scores > 2.3 are presented for most significantly correlated clusters. *Deactivated in a higher-level contrast analysis in comparison to itch condition. <sup><b><i>#</i></b></sup> Results of regression analyses performed for active scratching an itch are displayed. BA = Brodmann area; ACC = anterior cingulate cortex; PCC = posterior cingulate cortex; VTA = ventral tegmental area; PAG = periaqueductal gray; VPL= ventral posterolateral nucleus; VPM = ventral posteromedial nucleus; AN = anterior nucleus; LON = lateral posterior nucleus; LDN = lateral dorsal nucleus; MD = mediodorsal nucleus.</p> <p>(DOCX)</p>