Schematic overview of the models used for simulation. Eduard J. Kerkhoven Fiona Achcar Vincent P. Alibu Richard J. Burchmore Ian H. Gilbert Maciej TrybiƂo Nicole N. Driessen David Gilbert Rainer Breitling Barbara M. Bakker Michael P. Barrett 10.1371/journal.pcbi.1003371.g001 https://plos.figshare.com/articles/figure/Schematic_overview_of_the_models_used_for_simulation_/869000 <p>(<i>A</i>) Detailed scheme of the modeled metabolic pathways. The numbered arrows correspond to reactions from <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003371#pcbi-1003371-t001" target="_blank">Table 1</a>. Extensions to the original model of glycolysis are indicated by colored shapes. Boundary metabolites are in bold, glycosomal Rib-5-P is a boundary metabolite in model C and D. (<i>B</i>) Schematic overview of the different models, each consisting of a unique combination of the colored modules described in (<i>A</i>) and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003371#pcbi-1003371-t001" target="_blank">Table 1</a>. Model C and D can alternatively utilize fructose (model C<sup>fru</sup> and D<sup>fru</sup>), but this branch is switched off unless specifically mentioned.</p> 2013-12-05 02:47:01 overview