The effects of oxytocin (OT) and oxytocin extended form (OT-GKR) on intracellular calcium levels measured in Fura-2-loaded H9c2 cells. Marek Jankowski Bogdan A. Danalache Eric Plante Ahmed Menaouar Maria Florian Ju Jing Tan Ryszard Grygorczyk Tom L. Broderick Jolanta Gutkowska 10.1371/journal.pone.0219205.g006 https://plos.figshare.com/articles/figure/The_effects_of_oxytocin_OT_and_oxytocin_extended_form_OT-GKR_on_intracellular_calcium_levels_measured_in_Fura-2-loaded_H9c2_cells_/8614562 <p>(A). Percentage of calcium-responsive cells counted per microscopic field after treatment with equimolar concentrations (10<sup>−6</sup> M) of OT and OT-GKR. (B) Kinetics of intracellular calcium levels normalized as the F340/F380 ratio in cells responding to OT-GKR and (C) in cells resistant to OT-GKR Data were obtained from 7 separate experiments. For (A), statistical analysis was performed using a Students t-test. Data are presented as mean ± SEM. ***: p<0.001, compared to OT-GKR-treated cells.</p> 2019-07-03 17:37:01 OT-GKR V 2 OT biosynthetic precursor forms OT-GK CHO cells overexpressing V 2 receptor EC AVP diuresi sodium excretion OTA receptor V 2 V 2 R antagonist V 2 R OT-G OTR