10.1371/journal.pone.0075992.g005 Ryan G. Coleman Ryan G. Coleman Michael Carchia Michael Carchia Teague Sterling Teague Sterling John J. Irwin John J. Irwin Brian K. Shoichet Brian K. Shoichet Enrichment changes with varying degrees of orientational sampling. Public Library of Science 2013 varying degrees orientational 2013-10-01 02:20:10 Figure https://plos.figshare.com/articles/figure/_Enrichment_changes_with_varying_degrees_of_orientational_sampling_/812345 <p>The effect of changing the desired number of match goals, or orientational samples, on the overall enrichment of ligands over matched decoys is shown. Three possibilities are shown, A & C) MAP Kinase-Activated Protein Kinase 2 (MAPK2), where the logAUC goes down with increased orientational sampling, above that is the difference in DOCK energies for ligands and decoys for that target. B & D) Protein Farnesyltransferase/Geranylgeranyltransferase Type I Alpha Subunit (FNTA), where the logAUC does not change significantly with increased orientational sampling, again the difference between the ligand and decoy energies is shown above in the upper right. E), GRIK1 is shown, where the logAUC goes up with increased orientational sampling.</p>