10.6084/m9.figshare.7949555.v2 Elisha Roberson Elisha Roberson Complement cascade diagram figshare 2019 complement complement cascade complement activation classical pathway lectin pathway alternative pathway C3 C5 membrane attack complex Animal Cell and Molecular Biology Animal Immunology Immunology Medicine 2019-05-06 20:57:49 Figure https://figshare.com/articles/figure/Complement_cascade_diagram/7949555 <div>This is a simplified diagram of complement activation resulting in the membrane attack complex. Regardless of the initial activation pathway, the majority of complement activation may be through the alternative pathway feedback loop.</div><div><br></div><div>High quality diagram based on Brodky 2009 diagrams.</div><div><br></div><div>Brodsky R. Paroxysmal nocturnal hemoglobinuria. In: Hoffman R, Benz EJ Jr, Shattil SJ, et al., editors. Hematology: Basic Principles and Practice. Philadelphia, PA: Churchill Livingstone; 2009. p. 385-394.</div><div><br></div>