10.6084/m9.figshare.7949555.v2
Elisha Roberson
Elisha
Roberson
Complement cascade diagram
figshare
2019
complement
complement cascade
complement activation
classical pathway
lectin pathway
alternative pathway
C3
C5
membrane attack complex
Animal Cell and Molecular Biology
Animal Immunology
Immunology
Medicine
2019-05-06 20:57:49
Figure
https://figshare.com/articles/figure/Complement_cascade_diagram/7949555
<div>This is a simplified diagram of complement activation resulting in the membrane attack complex. Regardless of the initial activation pathway, the majority of complement activation may be through the alternative pathway feedback loop.</div><div><br></div><div>High quality diagram based on Brodky 2009 diagrams.</div><div><br></div><div>Brodsky R. Paroxysmal nocturnal hemoglobinuria. In: Hoffman R, Benz EJ Jr, Shattil SJ, et al., editors. Hematology: Basic Principles and Practice. Philadelphia, PA: Churchill Livingstone; 2009. p. 385-394.</div><div><br></div>