TY - DATA T1 - Effects of replenishment of IL-13 in DSS-induced colitis. PY - 2013/08/28 AU - Md. Sharif Shajib AU - Huaqing Wang AU - Janice J. Kim AU - Ivana Sunjic AU - Jean-Eric Ghia AU - Emmanuel Denou AU - Matthew Collins AU - Judah A. Denburg AU - Waliul I. Khan UR - https://plos.figshare.com/articles/figure/_Effects_of_replenishment_of_IL_13_in_DSS_induced_colitis_/783119 DO - 10.1371/journal.pone.0072774.g006 L4 - https://ndownloader.figshare.com/files/1183533 KW - histology KW - immunology KW - Immune cells KW - monocytes KW - Immune system KW - cytokines KW - immunity KW - inflammation KW - Immune response KW - Model organisms KW - Animal models KW - mouse KW - Gastroenterology and hepatology KW - Inflammatory bowel disease KW - ulcerative colitis KW - replenishment KW - il-13 KW - dss-induced N2 - IL-13−/− mice were treated with rmIL-13 (2 µg/day) injections or vehicle. rmIL-13 treatment started 3 days prior to 5 days of 5% DSS treatment. All groups received 5% DSS in the drinking water to induce colitis. (A) DAI. (B) Macroscopic damage score (C) Histologic scores and (D) MPO activity. (i) and (ii) Representative light micrograph of an H&E-stained colonic section. DAI data represented as mean ± SEM from 4 mice; *represents statistical significance where p<0.05; a, b and c represents statistically significant difference in disease activity scores on days indicated, where p<0.05. ER -