10.1371/journal.pone.0071448.g010
Mikhail V. Matz
Mikhail
V. Matz
Rachel M. Wright
Rachel
M. Wright
James G. Scott
James
G. Scott
Comparison of the Bayesian method to the delta-delta-Ct method, reanalyzing data from [38].
Public Library of Science
2013
Biochemistry
Nucleic acids
dna
DNA amplification
Computational biology
Molecular genetics
gene expression
genetics
genomics
Functional genomics
Marine biology
corals
Molecular cell biology
bayesian
delta-delta-ct
reanalyzing
2013-08-19 02:36:51
Figure
https://plos.figshare.com/articles/figure/_Comparison_of_the_Bayesian_method_to_the_delta_delta_Ct_method_reanalyzing_data_from_38_/775824
<p>(a) Fold-changes inferred by the naïve, informed and “classic” models plotted against fold-changes derived by the delta-delta-Ct analysis with a single control gene. (b) Comparison of p-values derived by the Bayesian z-test from naïve, informed, and “classic” models (see legend on panel a) with p-values obtained by pairwise t-tests within the delta-delta-Ct pipeline. On both panels, the line denotes 1∶1 correspondence. On panel b, points above the line indicate higher power (lower p-values) of the new models.</p>