Bandyopadhyay, Sanghamitra Cahill, Catherine Balleidier, Amelie Huang, Conan K. Lahiri, Debomoy Huang, Xudong T. Rogers, Jack Comparative IC<sub>50</sub> of JTR-009 relative to posiphen to inhibit APP 5′UTR driven luciferase expression relative to suppression of APP and Aβ levels in SH-SY5Y cells and primary neurons. <p>Comparative IC<sub>50</sub> of JTR-009 relative to posiphen to inhibit APP 5′UTR driven luciferase expression relative to suppression of APP and Aβ levels in SH-SY5Y cells and primary neurons.</p> Biochemistry;Nucleic acids;rna;proteins;genetics;Molecular cell biology;Cellular types;neurons;gene expression;Protein translation;nanotechnology;ferritin;Clinical genetics;Chromosomal disorders;Down syndrome;neurology;dementia;Alzheimer disease;jtr-009;posiphen;inhibit;app;driven;luciferase;suppression;sh-sy5y;cells 2013-07-31
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10.1371/journal.pone.0065978.t002