%0 Generic %A Hobiger, Kirstin %A Utesch, Tillmann %A Mroginski, Maria Andrea %A Seebohm, Guiscard %A Friedrich, Thomas %D 2013 %T Mutations in the TI-loop affect the number of contacts with the linker during the MD simulation. %U https://plos.figshare.com/articles/dataset/_Mutations_in_the_TI_loop_affect_the_number_of_contacts_with_the_linker_during_the_MD_simulation_/759329 %R 10.1371/journal.pone.0070272.t001 %2 https://ndownloader.figshare.com/files/1136422 %K Anatomy and physiology %K electrophysiology %K biophysics %K Biophysics simulations %K Computational biology %K Macromolecular structure analysis %K protein structure %K Molecular cell biology %K Signal transduction %K Signaling cascades %K Phospholipid signaling cascade %K Polyphosphoinositide signaling cascade %K Signaling in cellular processes %K Lipid signaling %K Transmembrane signaling %K Signaling in selected disciplines %K Neurological signaling %K Oncogenic signaling %K Signaling pathways %K Phosphoinositide signal transduction %K Mechanisms of signal transduction %K neuroscience %K Cellular neuroscience %K ion channels %K ti-loop %K contacts %K linker %K md %X

Interactions between the complete linker, its N- and C-terminal parts (240–249 and 250–257, respectively), K252, R253 and Y255 with the TI loop are summarized in terms of average contacts during the last 30 ns of simulation. Contacts are defined as atoms within a sphere of 3.5 Å.

%I PLOS ONE