TY - DATA T1 - Other GPi-s also induce UCP2 expression in HepG2 cells. PY - 2013/07/25 AU - Lilla Nagy AU - Tibor Docsa AU - Magdolna Szántó AU - Attila Brunyánszki AU - Csaba Hegedűs AU - Judit Márton AU - Bálint Kónya AU - László Virág AU - László Somsák AU - Pál Gergely AU - Péter Bai UR - https://plos.figshare.com/articles/figure/_Other_GPi_s_also_induce_UCP2_expression_in_HepG2_cells_/755547 DO - 10.1371/journal.pone.0069420.g005 L4 - https://ndownloader.figshare.com/files/1131624 KW - Biochemistry KW - metabolism KW - Carbohydrate metabolism KW - Metabolic pathways KW - drug discovery KW - glycobiology KW - Model organisms KW - Animal models KW - mouse KW - Molecular cell biology KW - Cellular stress responses KW - Clinical research design KW - Animal models of disease KW - Drugs and devices KW - Drug research and development KW - Endocrinology KW - Diabetic endocrinology KW - Diabetes mellitus type 2 KW - gpi-s KW - induce KW - ucp2 KW - hepg2 N2 - (A) Three GPi-s TH, NV50 and NV76 were tested on HepG2 cells. (B–C) HepG2 cells (n = 3) kept under normoglycemic conditions were treated with the inhibitors at the indicated concentrations for 8 hours, then (B) glycogen content and (C) UCP-2 expression was determined as described in Materials and Methods. Error is given as SD throughout the figure. * and *** indicate statistically significant difference between vehicle and GPi-treated groups at p<0.05, or p<0.001, respectively. VEH – vehicle, other abbreviations are in the text. ER -