10.1371/journal.ppat.1003530.g005
Muhamuda Kader
Muhamuda
Kader
Amanda P. Smith
Amanda
P. Smith
Cristiana Guiducci
Cristiana
Guiducci
Elizabeth R. Wonderlich
Elizabeth
R. Wonderlich
Daniel Normolle
Daniel
Normolle
Simon C. Watkins
Simon C.
Watkins
Franck J. Barrat
Franck
J. Barrat
Simon M. Barratt-Boyes
Simon
M. Barratt-Boyes
mDC gain the capacity to secrete IFN-α upon virus stimulation following SIV infection.
Public Library of Science
2013
Infectious diseases
Viral diseases
hiv
secrete
stimulation
siv
2013-07-25 01:47:11
Figure
https://plos.figshare.com/articles/figure/_mDC_gain_the_capacity_to_secrete_IFN_945_upon_virus_stimulation_following_SIV_infection_/754827
<p>(A) Dot plots showing intracellular IFN-α expression in blood mDC from untreated and DV056-treated macaques at day 0 and day 14 post infection after iSIV stimulation. Data for all animals are shown, along with a representative dot plot of cells exposed to control microvesicles. Flow cytometric gating to define mDC was done as in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003530#ppat-1003530-g001" target="_blank">Figure 1</a>. (B) Percent of blood mDC producing IFN-α after iSIV stimulation at the indicated times after infection in untreated and DV056-treated macaques. *<i>P</i><.05, **<i>P</i><.01.</p>