Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy-4 Pauline Chugh Birgit Bradel-Tretheway Carlos MR Monteiro-Filho Vicente Planelles Sanjay B Maggirwar Stephen Dewhurst Baek Kim 10.6084/m9.figshare.74694.v1 https://figshare.com/articles/figure/Akt_inhibitors_as_an_HIV-1_infected_macrophage-specific_anti-viral_therapy-4/74694 SIV mac239 and SIV PBJ. Numbers indicate residues on the first amino acids of the shown sequences. Colored residues in HIV-1 Tat were mutated in this study. CHME5 cells were cotransfected with a plasmid encoding GFP and constructs expressing the first exon of HIV-1 Tat (psvTat72), SIV-PBJ Tat, or with an empty plasmid (pcDNA3.1) using Lipofectamine. Cells were then treated with LPS/CHX and analyzed for cell death. Bright fields (BF) and merged (red+green) fields are shown. Transfected cells are GFP+ cells (green), dead cells (red). The percentage of cell death induced in GFP+, EthD+ cells is shown with the SD from three independent experiments.<p><b>Copyright information:</b></p><p>Taken from "Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy"</p><p>http://www.retrovirology.com/content/5/1/11</p><p>Retrovirology 2008;5():11-11.</p><p>Published online 31 Jan 2008</p><p>PMCID:PMC2265748.</p><p></p> 2011-12-31 14:33:51 akt inhibitors infected macrophagespecific antiviral