10.1371/journal.pmed.1001484.t003
Frédéric B. Piel
Frédéric
B. Piel
Simon I. Hay
Simon
I. Hay
Sunetra Gupta
Sunetra
Gupta
David J. Weatherall
David
J. Weatherall
Thomas N. Williams
Thomas
N. Williams
Projected number of newborns with SCA born in 2010 and 2050 for the three most affected countries (Nigeria, India, and the DRC), WHO regions, HbS regions, and worldwide.
Public Library of Science
2013
genetics
Human genetics
Genetic counseling
population genetics
geography
Human geography
Spatial analysis
Cartography
epidemiology
Disease mapping
Genetic epidemiology
Spatial epidemiology
Global health
hematology
Hemoglobinopathies
Sickle cell disease
Public health
Child health
Health screening
preventive medicine
newborns
sca
2010
2050
affected
countries
hbs
2013-07-16 03:18:22
Dataset
https://plos.figshare.com/articles/dataset/_Projected_number_of_newborns_with_SCA_born_in_2010_and_2050_for_the_three_most_affected_countries_Nigeria_India_and_the_DRC_WHO_regions_HbS_regions_and_worldwide_/746661
<p>Complete data for all countries are presented in <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001484#pmed.1001484.s002" target="_blank">Table S1</a>. Proportions per category are indicated for the predicted newborns with SCA. Relative changes are shown within parentheses.</p>a<p>Calculated as the product between the median SCA frequency based on the model outputs described in Piel et al. <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001484#pmed.1001484-Piel2" target="_blank">[21]</a> and the births per year for 2010–2015 from the 2010 revision of the UN World Population Prospects <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001484#pmed.1001484-United1" target="_blank">[22]</a>.</p>b<p>CIs based on the interquartile range of the SCA frequency estimates and the low- and high-fertility variants for birth counts.</p>c<p>Calculated as the product between the median SCA frequency based on the model outputs described in Piel et al. <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001484#pmed.1001484-Piel2" target="_blank">[21]</a>, assuming constant allele frequencies over the study period and using the data on births per year for 2050–2055 from the 2010 revision of the UN World Population Prospects <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001484#pmed.1001484-United1" target="_blank">[22]</a>.</p>d<p>Total estimated newborns with SCA born between 2010 and 2050.</p>e<p>As defined at <a href="http://www.who.int/about/regions/en/index.html" target="_blank">http://www.who.int/about/regions/en/index.html</a>. AFRO, African Region; AMRO, Region of the Americas; EMRO, Eastern Mediterranean Region; EURO, European Region; SEARO, Southeast Asia Region; WPRO, Western Pacific Region.</p>f<p>As shown in Web Figure 8 of Web Appendix 2 of Piel et al. <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001484#pmed.1001484-Piel2" target="_blank">[21]</a>.</p>