%0 Figure %A van Leeuwen, Marcella %A J. Kemna, Michael %A P. J. de Winther, Menno %A Boon, Louis %A M. Duijvestijn, Adriaan %A Henatsch, Darius %A A. Bos, Nico %A J. J. Gijbels, Marion %A Willem Cohen Tervaert, Jan %D 2013 %T IgM Monoclonal antibody (Moab A7S8). %U https://plos.figshare.com/articles/figure/_IgM_Monoclonal_antibody_Moab_A7S8_/746600 %R 10.1371/journal.pone.0068039.g002 %2 https://ndownloader.figshare.com/files/1120347 %K Model organisms %K Animal models %K mouse %K cardiovascular %K atherosclerosis %K Clinical immunology %K immunity %K immunizations %K inflammation %K immunoglobulins %K monoclonal %K antibody %X

A. Reactivity to native, HOCL-oxLDL and MDA-oxLDL. Measured by ELISA, OD 405 at different concentrations (100, 50, 25, 10 and 1 µg/ml IgM concentration). B. Sequence IgM hybridoma. The sequence of Moab A7S8 was compared with germline VH genes by using the international ImMunoGeneTics information system/−QUEry and Standardization (IMGT/V-Quest). Moab A7S8 is composed of IgHV1–78*01, IGHJ3*01 and IGHD1-1*02 alleles, with 100% identity and no gaps. Except for the N-addition, the alleles are in frame germline sequences.

%I PLOS ONE