Phenanthroline‑<i><sup>t</sup></i>BuOK Promoted Intramolecular C–H Arylation of Indoles with ArI under Transition-Metal-Free Conditions Xiang-Huan Shan Bo Yang Hong-Xing Zheng Jian-Ping Qu Yan-Biao Kang 10.1021/acs.orglett.8b03449.s001 https://acs.figshare.com/articles/journal_contribution/Phenanthroline_i_sup_t_sup_i_BuOK_Promoted_Intramolecular_C_H_Arylation_of_Indoles_with_ArI_under_Transition-Metal-Free_Conditions/7429481 The first example of phenanthroline-<i><sup>t</sup></i>BuOK promoted intramolecular radical C–H arylation of <i>N</i>-(2-iodobenzyl)­indoles without involvement of transition metals has been developed. A variety of substituted 6<i>H</i>-isoindolo [2, 1-a] indoles were prepared by a simple and efficient intramolecular cyclization using 1,10-phenanthroline in the presence of potassium <i>tert-</i>butoxide and chlorobenzene. This strategy provides a fast and versatile access to isoindolo­[2,1-<i>a</i>]­indole derivatives for the synthesis of pharmaceuticals and organic electroluminescent (EL) materials. 2018-12-06 13:19:00 Indole potassium tert phenanthroline chlorobenzene transition metals indole Arylation variety isoindolo access strategy electroluminescent derivative synthesis EL arylation pharmaceutical Transition-Metal-Free Conditions presence material 6 H t BuOK Promoted ArI intramolecular cyclization Phenanthroline butoxide iodobenzyl Intramolecular involvement 1-