%0 Journal Article %A Cesaretti, Alessio %A Di Guida, Irene %A Caldero-Rodríguez, Naishka E. %A Clementi, Catia %A Germani, Raimondo %A Gentili, Pier Luigi %D 2018 %T Mimicking the Secretory Action of a Gland by a Composite System Made of a pH-Responsive Surfactant-Based Hydrogel and a Dialysis Membrane %U https://acs.figshare.com/articles/journal_contribution/Mimicking_the_Secretory_Action_of_a_Gland_by_a_Composite_System_Made_of_a_pH-Responsive_Surfactant-Based_Hydrogel_and_a_Dialysis_Membrane/7429025 %R 10.1021/acsomega.8b02940.s001 %2 https://ndownloader.figshare.com/files/13755434 %K core %K pyridinium %K pulse %K acridinium %K Membrane %K acid %K hydrogel %K zwitterionic N-oxide surfactant %K monitoring %K dialysis %K Composite %K pH-Responsive Surfactant-Based Hydrogel %K alizarin %K gland model %K pH-responsive %K membrane %K Dialysi %K release %K Mimicking %K viscosity %K variation %K Secretory %K Gland %K secretory %X The hydrogel obtained by a zwitterionic N-oxide surfactant is proposed as the core of a pH-responsive artificial gland model. The viscosity and pH variations, induced by pulse additions of acid and base, are investigated by a pyridinium salt and alizarin red S, respectively. The artificial gland model is implemented by enclosing the gel within a dialysis membrane, and its secretory action is tested by monitoring the release of a fluorescent acridinium salt. %I ACS Publications