Spatial variation in phosphagens concentration in cross section 1.
Shouryadipta Ghosh
Kenneth Tran
Lea M. D. Delbridge
Anthony J. R. Hickey
Eric Hanssen
Edmund J. Crampin
Vijay Rajagopal
10.1371/journal.pcbi.1006640.g006
https://plos.figshare.com/articles/figure/Spatial_variation_in_phosphagens_concentration_in_cross_section_1_/7427324
<p>(A): Phosphagen concentrations were calculated at all the myofibril points in the mesh and subtracted from the spatially averaged concentration of each phosphagen (Phosg<sub>ave</sub>). Box plots represent the statistical distribution of the difference between phosphagen concentration at each point and Phosg<sub>ave</sub> value of each phosphagen. The zero value corresponds to the Phosg<sub>ave</sub>. (B): Normalized concentration of PCr and Cr displayed as a function of local mitochondrial density at various points in the cell. PCr and Cr concentrations were normalized by a factor equivalent to the difference of PCr and Cr maximum and minimum concentrations in cross section 1.</p>
2018-12-05 19:09:30
mitochondrial CK enzymes
impact
electron microscope images
metabolite distributions
creatine phosphate
bioenergetic
mitochondria aggregated
mitochondrial distributions
force production
mitochondrial arrangement
twitch duration
reactions act
cell cross-section
cell architecture
force dynamics
mitochondrial organization
uniform force dynamics
diffusion
hypoxia activity
uniform ATP
creatine kinase
element modeling
electron microscopy data
PCr shuttle
mitochondrial organisation
force generation
ADP ratios
phosphate compounds