Spatial variation in model predicted cytosolic phosphagen levels and reaction rates represented using colour spectrum.
Shouryadipta Ghosh
Kenneth Tran
Lea M. D. Delbridge
Anthony J. R. Hickey
Eric Hanssen
Edmund J. Crampin
Vijay Rajagopal
10.1371/journal.pcbi.1006640.g005
https://plos.figshare.com/articles/figure/Spatial_variation_in_model_predicted_cytosolic_phosphagen_levels_and_reaction_rates_represented_using_colour_spectrum_/7427321
<p>All the figures were generated by using the same range of colour spectrum for a particular phosphagen. (A-C): EM images of sections 1–3 (D-F): Distribution of ADP and ATP in the cross-sections represented using the ADP/ATP ratio. The ADP/ATP ratio remains uniform throughout the cross-sections (G-I): Inorganic phosphate (Pi) shows large spatial variation at the order of 1 mM. (J-L): Spatial variation in the ATP hydrolysis rate in the myofibrils corresponding to X<sub>ATPase</sub> = 0.05 <b>μ</b>M/sec.</p>
2018-12-05 19:09:30
mitochondrial CK enzymes
impact
electron microscope images
metabolite distributions
creatine phosphate
bioenergetic
mitochondria aggregated
mitochondrial distributions
force production
mitochondrial arrangement
twitch duration
reactions act
cell cross-section
cell architecture
force dynamics
mitochondrial organization
uniform force dynamics
diffusion
hypoxia activity
uniform ATP
creatine kinase
element modeling
electron microscopy data
PCr shuttle
mitochondrial organisation
force generation
ADP ratios
phosphate compounds