Spatial variation in model predicted cytosolic phosphagen levels and reaction rates represented using colour spectrum. Shouryadipta Ghosh Kenneth Tran Lea M. D. Delbridge Anthony J. R. Hickey Eric Hanssen Edmund J. Crampin Vijay Rajagopal 10.1371/journal.pcbi.1006640.g005 https://plos.figshare.com/articles/figure/Spatial_variation_in_model_predicted_cytosolic_phosphagen_levels_and_reaction_rates_represented_using_colour_spectrum_/7427321 <p>All the figures were generated by using the same range of colour spectrum for a particular phosphagen. (A-C): EM images of sections 1–3 (D-F): Distribution of ADP and ATP in the cross-sections represented using the ADP/ATP ratio. The ADP/ATP ratio remains uniform throughout the cross-sections (G-I): Inorganic phosphate (Pi) shows large spatial variation at the order of 1 mM. (J-L): Spatial variation in the ATP hydrolysis rate in the myofibrils corresponding to X<sub>ATPase</sub> = 0.05 <b>μ</b>M/sec.</p> 2018-12-05 19:09:30 mitochondrial CK enzymes impact electron microscope images metabolite distributions creatine phosphate bioenergetic mitochondria aggregated mitochondrial distributions force production mitochondrial arrangement twitch duration reactions act cell cross-section cell architecture force dynamics mitochondrial organization uniform force dynamics diffusion hypoxia activity uniform ATP creatine kinase element modeling electron microscopy data PCr shuttle mitochondrial organisation force generation ADP ratios phosphate compounds