Model assumptions and FE mesh generation from EM image cross-sections.
Shouryadipta Ghosh
Kenneth Tran
Lea M. D. Delbridge
Anthony J. R. Hickey
Eric Hanssen
Edmund J. Crampin
Vijay Rajagopal
10.1371/journal.pcbi.1006640.g003
https://plos.figshare.com/articles/figure/Model_assumptions_and_FE_mesh_generation_from_EM_image_cross-sections_/7427315
<p>(A): We assumed that individual mitochondria that cluster together will share a common inner membrane space. (B): Based on this assumption, each mitochondrial cluster was divided into two regions: an IMS region, depicted in green and a matrix region, depicted in blue. A third region depicted in red covers the myofibrils present in the cell. (C): Image of a FE mesh developed from the EM image of cross-section 1 with the three different regions.</p>
2018-12-05 19:09:30
mitochondrial CK enzymes
impact
electron microscope images
metabolite distributions
creatine phosphate
bioenergetic
mitochondria aggregated
mitochondrial distributions
force production
mitochondrial arrangement
twitch duration
reactions act
cell cross-section
cell architecture
force dynamics
mitochondrial organization
uniform force dynamics
diffusion
hypoxia activity
uniform ATP
creatine kinase
element modeling
electron microscopy data
PCr shuttle
mitochondrial organisation
force generation
ADP ratios
phosphate compounds