EM image of a single cardiac myocyte. Shouryadipta Ghosh Kenneth Tran Lea M. D. Delbridge Anthony J. R. Hickey Eric Hanssen Edmund J. Crampin Vijay Rajagopal 10.1371/journal.pcbi.1006640.g001 https://plos.figshare.com/articles/figure/EM_image_of_a_single_cardiac_myocyte_/7427309 <p>(A): A Longitudinal section from the SBF-SEM images of a single cardiomyocyte with mitochondria in dark regions and myofibril/nucleus in light regions. (B-D): Cross sections (1–3) corresponding to the location of three white dotted lines in the longitudinal section. Section 1 is located near a branching point, and section 2 is located close to a nucleus, however none of the sections contain a nucleus.</p> 2018-12-05 19:09:30 mitochondrial CK enzymes impact electron microscope images metabolite distributions creatine phosphate bioenergetic mitochondria aggregated mitochondrial distributions force production mitochondrial arrangement twitch duration reactions act cell cross-section cell architecture force dynamics mitochondrial organization uniform force dynamics diffusion hypoxia activity uniform ATP creatine kinase element modeling electron microscopy data PCr shuttle mitochondrial organisation force generation ADP ratios phosphate compounds