10.26180/5c062a4d4d0ea
AMY YI HSAN SAIK
AMY YI HSAN
SAIK
Biosynthesis of Acylated Quercetin Analogues via Lipases and Investigation of their Cytotoxicity in Human Cancer Cells
Monash University
2018
Quercetin
Enzymatic acylation
Cinnamic acid
Oleic acid
Palmitic acid
Cytotoxicity
Colon cancer cells
Oral cancer cells
Lipases
Flavonoids
Biocatalysis and Enzyme Technology
2018-12-04 07:18:35
Thesis
https://bridges.monash.edu/articles/thesis/Biosynthesis_of_Acylated_Quercetin_Analogues_via_Lipases_and_Investigation_of_their_Cytotoxicity_in_Human_Cancer_Cells/7415231
This thesis examines the enzymatic modification of quercetin with cinnamic, oleic or palmitic acid. It identifies the lipophilicity, solubility, stability and cytotoxicity of the newly formed acylated quercetin analogues against human colon and oral cancer cells.