10.6084/m9.figshare.7314509.v1
Renate Kristianslund
Renate
Kristianslund
Anders Vik
Anders
Vik
Trond V. Hansen
Trond V.
Hansen
A convenient synthesis of phenols
Taylor & Francis Group
2018
Anilines
copper sulfate
diazotization
3-iodo catechol
phenols
2018-11-08 10:36:18
Journal contribution
https://tandf.figshare.com/articles/journal_contribution/A_convenient_synthesis_of_phenols/7314509
<p>Anilines are rapidly, often within 60 minutes, converted into the corresponding phenols in up to 87% isolated yield. The presented experimentally simple protocol display broad compatibility with a variety of functional groups, and in particular, well suited for the preparation of methyl-substituted phenols. Such phenols are not easily available by other synthetic approaches. The formation of phenolic radical coupling products was not observed even for activated anilines using this open flask method.</p>