Dataset for: The gut microbiome participates in transgenerational inheritance of low temperature responses in <i>Drosophila melanogaster</i>
Aman Zare
Anna-mia Johansson
Edvin Karlsson
Nicolas Delhomme
Per Stenberg
10.6084/m9.figshare.7252529.v1
https://wiley.figshare.com/articles/dataset/Dataset_for_The_gut_microbiome_participates_in_transgenerational_inheritance_of_low_temperature_responses_in_i_Drosophila_melanogaster_i_/7252529
Environmental perturbations induce transcriptional changes, some of which may be inherited even in the absence of the initial stimulus. Previous studies have focused on transfers through the germ-line although microbiota is also passed on to the offspring. Thus, we inspected the involvement of the gut microbiome in transgenerational inheritance of environmental exposures in <i>Drosophila melanogaster.</i> We grew flies in the cold versus control temperatures and compared their transcriptional patterns in both conditions as well as in their offspring. F2 flies grew in control temperature while we controlled their microbiota acquisition from either F1 sets. Transcriptional status of some genes was conserved transgenerationally, and a subset of these genes, mainly expressed in the gut, was transcriptionally dependent on the acquired microbiome.
2018-11-15 08:52:13
Drosophila melanogaster
gut microbiota
host microbiome interaction
environmental response
Biophysics
Synthetic Biology
Biochemistry
Plant Biology
Virology
Receptors and Membrane Biology
Computational Biology
Immunology
Neuroscience
Cell Development, Proliferation and Death
Molecular Biology
Evolutionary Biology
Signal Transduction
Cancer Cell Biology
Systems Biology
Structural Biology