%0 Figure %A Seifert, Robert %A Kuhlmann, Michael T. %A Eligehausen, Sarah %A Kiefer, Friedemann %A Hermann, Sven %A Schäfers, Michael %D 2018 %T Histological and ELISA analysis of carotid arteries. %U https://plos.figshare.com/articles/figure/Histological_and_ELISA_analysis_of_carotid_arteries_/7192895 %R 10.1371/journal.pone.0204305.g005 %2 https://ndownloader.figshare.com/files/13243385 %K CCA %K MMP -9 activities %K plaque phenotypes %K MMP -2 concentrations %K MMP activity discriminates %K DS plaques %K shear stress-induced atherosclerosis %K MMP -2 %K MMP inhibitor-based fluorescence %K vivo fluorescence reflectance imaging %K murine atherosclerosis Purpose %K atherosclerotic plaque ruptures %K ELISA %K 1.06 plaque-to-background ratio %K MMP -9 concentrations %K MMP inhibitor-based photoprobe Cy 5.5-AF %X

Semi-quantitative intensity scores of the MMP-2, MMP-9, MRP14 and Mac-3 staining (n = 5) displayed as summed group score for DS, US and inside cuff regions (A). The summed group score is calculated by adding together the consensus reading results of all 5 animals, visualizing the results with respect to the performed staining and region (US, cuff or DS). Total MMP-2 (B) and MMP-9 (C) concentration normalised to protein level of right CCA US and DS region (n = 13) and left CCA as control (n = 14).

%I PLOS ONE