10.1371/journal.pone.0061984.g004
Cong Yan
Cong
Yan
Xinchun Ding
Xinchun
Ding
Lingyan Wu
Lingyan
Wu
Menggang Yu
Menggang
Yu
Peng Qu
Peng
Qu
Hong Du
Hong
Du
ELISA analyses of CHI3L1 protein in BALF and serum of systemic inflammation-induced lung tumor mice.
Public Library of Science
2013
Biochemistry
histology
immunology
oncology
Cancer detection and diagnosis
Early detection
chi3l1
balf
serum
systemic
inflammation-induced
2013-04-22 02:11:12
Figure
https://plos.figshare.com/articles/figure/_ELISA_analyses_of_CHI3L1_protein_in_BALF_and_serum_of_systemic_inflammation_induced_lung_tumor_mice_/687872
<p>Left: CHI3L1 protein concentrations in BALF and serum of doxycycline-treated and untreated bitransgenic mice. Right: ROC (Receiver Operating Characteristic) curve analyses to determine the area under the curve (AUC). Dox-: doxycycline-untreated mice; Dox+: doxycycline-treated mice without showing lung tumor; Cancer, doxycycline-treated mice with lung tumor. <b>A)</b> c-fms-rtTA/(TetO)<sub>7</sub>-CMV-MMP12 mice. Mean ± SD in BALF (n>7), DOX -: 17.7±13.8, DOX +: 42.1±67.9, Cancer: 70.9±36.5. Mean ± SD in serum (n>7), DOX -: 39.1±25.6, DOX +: 57.7±55.5, Cancer: 232.3±110.6. The gray lines represent the mean values; <b>B)</b> c-fms-rtTA/(TetO)<sub>7</sub>-CMV-Api6 mice. Mean ± SD in BALF (n>6), DOX -: 69.6±16.6, DOX +: 73.2±28.1, Cancer: 189.9±47.2. Mean ± SD in serum (n>6), DOX -: 25.2±7.3, DOX +: 21.0±11.7, Cancer: 69.5±19.1. The gray lines represent the mean values.</p>