TY - DATA T1 - Iron-catalyzed deoxygenation and 2-sulfonylation of quinoline N-oxides by sodium sulfinates towards 2-sulfonyl quinolines PY - 2018/07/11 AU - Ping Li AU - Yangji Jiang AU - Han Li AU - Wanrong Dong AU - Zhihong Peng AU - Delie An UR - https://tandf.figshare.com/articles/journal_contribution/Iron-catalyzed_deoxygenation_and_2-sulfonylation_of_quinoline_i_N_i_-oxides_by_sodium_sulfinates_towards_2-sulfonyl_quinolines/6804650 DO - 10.6084/m9.figshare.6804650.v1 L4 - https://ndownloader.figshare.com/files/12375890 KW - Iron catalysis KW - deoxygenation KW - 2-sulfonylation KW - quinoline N-oxides KW - sodium sulfinates N2 - An iron(III)-catalyzed protocol towards 2-sulfonyl quinolines from quinoline N-oxides and sodium sulfinates was herein illustrated. The general and direct option featured for high efficiency (up to 91% yields) and good functional compatibilities (27 examples) in the Fe(III)-catalysis. Moreover, free radical mechanism was proposed for the one-pot deoxygenation and sulfonylation reaction based on the results of the control reactions. An novel reaction between quinoline N-oxides and sodium sulfinates for the synthesis of 2-sulfonyl quinolines was herein achieved by an iron(III)-catalyzed system. The general and direct transformation exhibited high efficiency (up to 91% yields) and good functional-groups compatibilities (27 examples). Moreover, free radical mechanism was proposed for the one-pot deoxygenation and sulfonylation reaction based on the results of the control reactions. ER -