TY - DATA T1 - The cytoskeleton disrupting agent latruculin A induces reactivation of FPR1des. PY - 2013/03/29 AU - Huamei Forsman AU - Karin Önnheim AU - Emil Andréasson AU - Karin Christenson AU - Anna Karlsson AU - Johan Bylund AU - Claes Dahlgren UR - https://plos.figshare.com/articles/figure/_The_cytoskeleton_disrupting_agent_latruculin_A_induces_reactivation_of_FPR1_des_/661928 DO - 10.1371/journal.pone.0060169.g005 L4 - https://ndownloader.figshare.com/files/1000151 KW - cytoskeleton KW - disrupting KW - latruculin KW - reactivation N2 - Latrunculin A (100 ng/ml) was added to FPR1des neutrophils (105 cells; desensitized with 0.1 nM fMIFL) in the absence (solid line) or presence (dotted line) of cyclosporin H (1 µM, FPR1 specific antagonist, added 1 min before latrunculin A) and the release of superoxide anions was determined. For comparison, a PAF-induced reactivation of FPR1des neutrophils is included (dashed line). A representative experiment is shown, n>5. Abscissa, time of study (min); Ordinate, superoxide production (counts per minute×106; Mcpm). ER -