10.1371/journal.pbio.0040261.g004
Elena O Gracheva
Elena
O Gracheva
Anna O Burdina
Anna
O Burdina
Andrea M Holgado
Andrea
M Holgado
Martine Berthelot-Grosjean
Martine
Berthelot-Grosjean
Brian D Ackley
Brian
D Ackley
Gayla Hadwiger
Gayla
Hadwiger
Michael L Nonet
Michael
L Nonet
Robby M Weimer
Robby
M Weimer
Janet E Richmond
Janet
E Richmond
tom-1(ok285) Mutants Accumulate Vesicles That Are Contacting the Plasma Membrane
Public Library of Science
2013
mutants
accumulate
vesicles
contacting
plasma
2013-02-22 08:35:39
Figure
https://plos.figshare.com/articles/figure/_tom_1_ok285_Mutants_Accumulate_Vesicles_That_Are_Contacting_the_Plasma_Membrane_/628457
<div><p>(A) Examples of synaptic profiles from WT and
<i>tom-1(ok285)</i> neuromuscular synapse prepared by high-pressure freeze and freeze substitution. The presynaptic density is labeled PD, and the plasma membrane-contacting vesicles are indicated with arrows. Scale bar, 100 nm.
</p>
<p>(B) Vesicles contacting the plasma membrane as a ratio of total vesicles per synaptic profile are increased in
<i>tom-1(ok285)</i> mutant animals.
</p>
<p>(C) The distribution of plasma membrane-contacting vesicles relative to the presynaptic density, expressed in 30-nm bins as a ratio of total vesicles per profile for WT and
<i>tom-1(ok285).</i></p>
<p>(D) Schematic representation of data in (C) depicting the distribution of vesicles contacting plasma membrane (black circles for WT, purple circles for
<i>tom-1</i> mutants) relative to the presynaptic density. Data expressed as mean ± SEM.
</p></div>