Magnetoreception of Photoactivated
Cryptochrome 1
in Electrochemistry and Electron Transfer
Zheng Zeng
Jianjun Wei
Yiyang Liu
Wendi Zhang
Taylor Mabe
10.1021/acsomega.8b00645.s001
https://acs.figshare.com/articles/journal_contribution/Magnetoreception_of_Photoactivated_Cryptochrome_1_in_Electrochemistry_and_Electron_Transfer/6205139
Cryptochromes
are flavoproteins whose photochemistry is important
for crucial functions associated with phototropism and circadian clocks.
In this report, we, for the first time, observed a magnetic response
of the cryptochrome 1 (CRY1) immobilized at a gold electrode with
illumination of blue light. These results present the magnetic field-enhanced
photoinduced electron transfer of CRY1 to the electrode by voltammetry,
exhibiting magnetic responsive rate constant and electrical current
changes. A mechanism of the electron transfer, which involves photoinduced
radicals in the CRY, is sensitive to the weak magnetic field; and
the long-lived free radical FAD<sup>•–</sup> is responsible
for the detected electrochemical Faradaic current. As a photoreceptor,
the finding of a 5.7% rate constant change in electron transfer corresponding
to a 50 μT magnetic field may be meaningful in regulation of
magnetic field signaling and circadian clock function under an electromagnetic
field.
2018-05-01 12:50:42
circadian clock function
electrode
field-enhanced photoinduced electron transfer
Photoactivated Cryptochrome 1
50 μ T
FAD
electron transfer
Electron Transfer Cryptochromes