%0 Figure %A Yang, Su-Rong %A Hu, Zhen-Zhen %A Luo, Yan-Jia %A Zhao, Ya-Nan %A Sun, Huan-Xin %A Yin, Dou %A Wang, Chen-Yao %A Yan, Yu-Dong %A Wang, Dian-Ru %A Yuan, Xiang-Shan %A Ye, Chen-Bo %A Guo, Wei %A Qu, Wei-Min %A Cherasse, Yoan %A Lazarus, Michael %A Ding, Yu-Qiang %A Huang, Zhi-Li %D 2018 %T Rats with RMTg lesions by ibotenic acid for 8 days showed a deficit in rebound of non-rapid eye movement (NREM) sleep quality in response to 6-hour sleep deprivation (SD). %U https://plos.figshare.com/articles/figure/Rats_with_RMTg_lesions_by_ibotenic_acid_for_8_days_showed_a_deficit_in_rebound_of_non-rapid_eye_movement_NREM_sleep_quality_in_response_to_6-hour_sleep_deprivation_SD_/6141446 %R 10.1371/journal.pbio.2002909.g007 %2 https://ndownloader.figshare.com/files/11216057 %K control rats %K 2- hour recovery period %K midbrain dopaminergic system %K baseline levels %K rat RMTg neurons %K midbrain dopaminergic neurons %K ventral tegmental area %K pharmacogenetic %K VTA %K NREM %K rostromedial tegmental nucleus %K SWA %K non-rapid eye movement %K lesion %K dorsal raphe nucleus %X

(A, B) Time course of NREM sleep in control (A) and RMTg lesioned rats (B). Sleep was deprived from 13:00 to 19:00 hours. (C, D) Amount of NREM sleep (C) and mean duration of NREM sleep (D) during 19:00–21:00 hours following 6-hour SD. (E, F) Time course of slow-wave activity (SWA) (expressed as percentage of delta power [0.5–4 Hz] in NREM sleep per hour) from 19:00 to 07:00 hours following 6-hour SD in control (E) and RMTg lesioned rats (F). *p < 0.05, **p < 0.01 versus corresponding baseline using 2-way ANOVA followed by paired t tests. Control (n = 6); lesion (n = 4). The horizontal open and filled bars on the x-axes indicate the 12-hour light and the 12-hour dark period, respectively. Underlying data can be found in S1 Data.

%I PLOS Biology