TY - DATA T1 - Recognition Sequence Conservation as a Function of Peak Intensity PY - 2008/02/12 AU - Xiao-yong Li AU - Stewart MacArthur AU - Richard Bourgon AU - David Nix AU - Daniel A Pollard AU - Venky N Iyer AU - Aaron Hechmer AU - Lisa Simirenko AU - Mark Stapleton AU - Cris L. Luengo Hendriks AU - Hou Cheng Chu AU - Nobuo Ogawa AU - William Inwood AU - Victor Sementchenko AU - Amy Beaton AU - Richard Weiszmann AU - Susan E Celniker AU - David W Knowles AU - Tom Gingeras AU - Terence P Speed AU - Michael B Eisen AU - Mark D Biggin UR - https://plos.figshare.com/articles/figure/_Recognition_Sequence_Conservation_as_a_Function_of_Peak_Intensity_/610067 DO - 10.1371/journal.pbio.0060027.g015 L4 - https://ndownloader.figshare.com/files/939652 KW - Biochemistry KW - developmental biology KW - genetics and genomics N2 - Conservation scores in predicted factor recognition sequences (p-value ≤ 0.001) (red lines), all remaining sequences (blue lines), and in sequences matching scrambled variants of the factors' recognition sequences (p-value ≤ 0.001) (green lines) in the 500-bp regions (±250 bp) around BCD1 and KR1 1% FDR peaks, in nonoverlapping windows of 250 peaks down the rank list to the 25% FDR cutoff. Panels in row (A) shows the mean PhastCons scores, and panels in row (B) the average pairwise differences per base pair between D. melanogaster and D. simulans. Gaps are ignored in the pairwise analysis. The 1% FDR cutoff is indicated by a vertical dotted line. ER -