%0 Figure %A Girinathan, Brintha Parasumanna %A Ou, Junjun %A Dupuy, Bruno %A Govind, Revathi %D 2018 %T SinRR’ positively influences the expression of PaLoC genes. %U https://plos.figshare.com/articles/figure/SinRR_positively_influences_the_expression_of_PaLoC_genes_/5974954 %R 10.1371/journal.ppat.1006940.g005 %2 https://ndownloader.figshare.com/files/10830089 %K SinR %K JIR %K sporulation %K strains R 20291 %K sin locus mutants %K 0A %K sin locus %K sin locus Clostridium %K target gene expression %K aa %K toxin production %X

(A) Quantification of toxins in parent R20291 and the sinRR’ mutant complemented strains using toxins specific ELISA. The data shown are means ± standard errors of three replicates. Statistical significance was tested using one-way ANOVA, followed by Dunnett’s multiple comparisons test comparing values to the average of the parent with vector control (*** <0.0005 p-value). (B) Increased intracellular levels of c-di-GMP in the sinRR’ mutant. Statistical analysis was performed using two-tailed t-test (* <0.05 p-value).

%I PLOS Pathogens