TY - DATA T1 - Immunohistochemistry of anti-CB2 antibody in spinal cord SRMA lesions. PY - 2018/02/06 AU - Jessica Freundt-Revilla AU - Franciska Heinrich AU - Alexander Zoerner AU - Felix Gesell AU - Martin Beyerbach AU - Merav Shamir AU - Anna Oevermann AU - Wolfgang Baumgärtner AU - Andrea Tipold UR - https://plos.figshare.com/articles/figure/Immunohistochemistry_of_anti-CB2_antibody_in_spinal_cord_SRMA_lesions_/5858808 DO - 10.1371/journal.pone.0187197.g004 L4 - https://ndownloader.figshare.com/files/10412697 KW - CNS diseases KW - Steroid-Responsive Meningitis-Arteritis KW - IHC KW - AEA KW - CB 2 receptor KW - SRMA KW - cannabinoid type 2 receptors KW - CSF KW - EC KW - upregulated endocannabinoid system KW - CB 2 receptor expression KW - AG KW - endocannabinoid system KW - glial cells KW - Intraspinal Spirocercosis Endocannabinoids KW - CB 2 receptor-dependent manner N2 - A) Strong CB2 positive perivascular inflammatory infiltrates surrounding meningeal blood vessels. B) The CB2 positive leukocyte population mainly consists of lymphocytes, plasma cells and fewer macrophages. C) Severe diffuse infiltration of the dura mater with CB2 positive inflammatory cells. D) Vacuolization of white matter areas with concomitant CB2 positive glial cells and leukocytes. IHC was performed using the avidin-biotin-peroxidase complex (ABC) method. ER -