Green synthesis and antioxidant activity of novel series of benzofurans from euparin extracted of <i>Petasites hybridus</i>
Elham Ezzatzadeh
Zinatossadat Hossaini
10.6084/m9.figshare.5830986.v1
https://tandf.figshare.com/articles/journal_contribution/Green_synthesis_and_antioxidant_activity_of_novel_series_of_benzofurans_from_euparin_extracted_of_i_Petasites_hybridus_i_/5830986
<p>A novel class of benzofuran derivatives is prepared from the isocyanide-based MCR, euparin and aldehydes in the presence of ZnO-nanorods as a catalyst in excellent yields at room temperature under solvent-free conditions as a green reaction medium. Also, the antioxidant activities of some synthesised compounds such as <b>4a</b>, <b>4b</b>, <b>10a</b> and <b>10b</b> were evaluated by DPPH radical scavenging and ferric reduction activity potential (FRAP) assays. Compound <b>10b</b>, was shown moderate radical scavenging activity and very good reducing activity compared to standards (BHT and TBHQ).</p>
2018-01-29 06:32:16
Benzofuran
isocyanide
ZnO-nanorods
three-component reaction
euparin