10.1371/journal.ppat.1006834.g007 Chunhong Yin Chunhong Yin Niluka Goonawardane Niluka Goonawardane Hazel Stewart Hazel Stewart Mark Harris Mark Harris V67A and P145A disrupted the co-localization between NS5A and Core or LDs. Public Library of Science 2018 JFH -1-derived sub-genomic replicon genome replication HCV lipid droplets NS 5A domain UTR P 35A V 67A virus genome replication virus assembly hepatitis C virus NS 5A protein hepatitis C virus V 67A NS 5A RNA density gradient fractionation NS 5A protein P 145A lipid droplet morphology III resolution confocal microscopy II 2018-01-19 19:05:42 Figure https://plos.figshare.com/articles/figure/V67A_and_P145A_disrupted_the_co-localization_between_NS5A_and_Core_or_LDs_/5806893 <p><b>A</b> Quantification of the percentages of NS5A colocalized with LD (white blocks), or LD colocalised with NS5A (red blocks). <b>B</b> Quantification of the percentages of NS5A colocalized with Core (white blocks), or Core colocalised with NS5A (green blocks). <b>C</b> Quantification of the percentages of Core colocalized with LD (green blocks), or LD colocalised with Core (red blocks). <b>D</b> Spatial data for the distance of LDs from the nuclear envelope were determined from 10 cells for each construct using Fiji. **** indicates significant difference (P<0.0001) from the results for WT.</p>