TY - DATA T1 - Cooperative Metal–Ligand Catalyzed Intramolecular Hydroamination and Hydroalkoxylation of Allenes Using a Stable Iron Catalyst PY - 2018/01/18 AU - Osama El-Sepelgy AU - Aleksandra Brzozowska AU - Jan Sklyaruk AU - Yoon Kyung Jang AU - Viktoriia Zubar AU - Magnus Rueping UR - https://acs.figshare.com/articles/journal_contribution/Cooperative_Metal_Ligand_Catalyzed_Intramolecular_Hydroamination_and_Hydroalkoxylation_of_Allenes_Using_a_Stable_Iron_Catalyst/5801256 DO - 10.1021/acs.orglett.7b03828.s001 L4 - https://ndownloader.figshare.com/files/10250166 KW - reaction conditions KW - Allene KW - hydroalkoxylation KW - Hydroamination KW - dihydropyrrole KW - iron-catalyzed chemoselective intramolecular hydroamination KW - moisture KW - allene KW - absence KW - activation KW - Stable Iron Catalyst KW - 5- membered heterocycles KW - Effective selectivity control KW - hydrofunctionalization KW - additive KW - Catalyzed KW - α- allenic amines KW - substrate KW - dihydrofuran KW - yield KW - Hydroalkoxylation KW - iron catalyst KW - Intramolecular KW - Cooperative N2 - A new iron-catalyzed chemoselective intramolecular hydroamination and hydroalkoxylation of the readily available α-allenic amines and alcohols to valuable unsaturated 5-membered heterocycles, 2,3-dihydropyrrole and 2,3-dihydrofuran, is reported. Effective selectivity control is achieved by a metal–ligand cooperative activation of the substrates. The mild reaction conditions and the use of low amounts of an air and moisture stable iron catalyst allow for the hydrofunctionalization of a wide range of allenes bearing different functional groups in good yields in the absence of base or any sensitive additives. ER -