Binding parameters of the interaction of GAPDH protein with piceatannol in water solution at 25°C determined by isothermal titration calorimetry.
Joanna Gerszon
Eligiusz Serafin
Adam Buczkowski
Sylwia Michlewska
Jakub Antoni Bielnicki
Aleksandra Rodacka
10.1371/journal.pone.0190656.t001
https://plos.figshare.com/articles/dataset/Binding_parameters_of_the_interaction_of_GAPDH_protein_with_piceatannol_in_water_solution_at_25_C_determined_by_isothermal_titration_calorimetry_/5755218
<p>Binding parameters of the interaction of GAPDH protein with piceatannol in water solution at 25°C determined by isothermal titration calorimetry.</p>
2018-01-03 18:39:11
oxidative modifications
nucleophilic cysteine residue
glyceraldehyde -3-phosphate dehydrogenase Glyceraldehyde -3-phosphate dehydrogenase
GAPDH aggregation
11 ligand binding positions
ITC
GAPDH piceatannol blocks cysteine residue
piceatannol decreases GAPDH activity
reactive cysteine residue