Far-UV CD spectra of native GAPDH and GAPDH treated with 32 μM of piceatannol at room temperature for 50 and 100 min of incubation.
Joanna Gerszon
Eligiusz Serafin
Adam Buczkowski
Sylwia Michlewska
Jakub Antoni Bielnicki
Aleksandra Rodacka
10.1371/journal.pone.0190656.g004
https://plos.figshare.com/articles/figure/Far-UV_CD_spectra_of_native_GAPDH_and_GAPDH_treated_with_32_M_of_piceatannol_at_room_temperature_for_50_and_100_min_of_incubation_/5755149
<p>The data are expressed as molar residue ellipticity.</p>
2018-01-03 18:39:11
oxidative modifications
nucleophilic cysteine residue
glyceraldehyde -3-phosphate dehydrogenase Glyceraldehyde -3-phosphate dehydrogenase
GAPDH aggregation
11 ligand binding positions
ITC
GAPDH piceatannol blocks cysteine residue
piceatannol decreases GAPDH activity
reactive cysteine residue