Regioselective Halogenation of Arenes and Heterocycles in Hexafluoroisopropanol Ren-Jin Tang Thierry Milcent Benoit Crousse 10.1021/acs.joc.7b02920.s001 https://acs.figshare.com/articles/journal_contribution/Regioselective_Halogenation_of_Arenes_and_Heterocycles_in_Hexafluoroisopropanol/5747193 Regioselective halogenation of arenes and heterocycles with <i>N</i>-halosuccinimides in fluorinated alcohols is disclosed. Under mild condition reactions, a wide diversity of halogenated arenes are obtained in good yields with high regioselectivity. Additionally, the versatility of the method is demonstrated by the development of one-pot sequential halogenation and halogenation-Suzuki cross-coupling reactions. 2017-12-19 00:00:00 one-pot sequential halogenation diversity condition reactions regioselectivity Heterocycle Hexafluoroisopropanol Regioselective halogenation halogenation-Suzuki cross-coupling reactions halosuccinimide Regioselective Halogenation method Arene heterocycle versatility arene yield